Here is a thorough list of everything ComputerBob have done to get Debian running on his computer and his experience with it.
Read it here
Here's what I'm thinking: If I can get Debian installed and configured (with KDE, not Gnome) before Mepis 7 comes out, I'll be able to “take it around the block.” If I think that I can “ride it well enough to get to work,” then I'll probably switch from using Mepis full-time to using Debian full-time. If it turns out that Debian is too much for me to handle, I'll happily keep using Mepis 6.5, and I'll probably upgrade to Mepis 7 Final whenever it gets released. Either way, It'll be completely up to me to choose whatever I feel comfortable doing, based on my current skills and knowledge. Vive libre!